Study on the pathogenesis of acute cerebrovascular disease

Date: 2019-04-09
Times of browsing: 4

Acute cerebrovascular disease is a sudden onset, repeated illness, and the patient's condition is prone to recurrence. The patient's electrocardiogram showed abnormal ECG results and laboratory damage to the myocardium. Some studies have shown that the electroencephalogram of acute cerebrovascular disease has specific changes, showing ST-T segment down, T wave low or inversion, Q-T interval prolongation, abnormal Q wave, arrhythmia and so on. A summary of relevant research is summarized below, as follows:

 

 Study on the pathogenesis of acute cerebrovascular disease

The causes of acute cerebrovascular disease are hypertension, atherosclerosis, and hyperlipidemia. Patients with acute cerebrovascular disease show myocardial ischemia and hypoxia, coronary arteriosclerosis and so on. The pathogenesis of acute cerebrovascular disease can be summarized as follows [1]: (1) After cerebral edema, the circulating pressure of the brain tissue increases, and there is some interference with the regulation ability of the hypothalamus, causing autonomic dysfunction of the body, and synthesis of catecholamines by nerve cells. The speed is increased, causing myocardial cells to undergo dissolved necrosis and reduced contractile function. The electrocardiogram showed a significant change in the T wave. Myocardial injury is also associated with increased cardiovascular activity and hyposympathetic regulation, aggravating myocardial damage. (2) increased intracranial pressure, can cause endocardial hemorrhage, increase vascular resistance, resulting in increased arterial pressure. (3) When an acute cerebrovascular disease occurs, the patient may exhibit central respiratory dysfunction, persistent hyperthermia, left shift of oxygen dissociation curve, etc., free radicals in the body, acid-base imbalance, and abnormal myocardial function. (4) When performing acute cerebrovascular disease, a large amount of dehydrating agent will be applied for a long time, which will also destroy the electrolyte balance in the body, resulting in loss of sodium and potassium ions, tissue hypoxia, and damage to the myocardium. (5) After sudden acute cerebrovascular disease, the use of blood clotting agents to stop bleeding, so that the blood in the body is in a hypercoagulable state, aggravating myocardial load.


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